PiRNA

Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex

Xiawei Huang, Hongmiao Hu, Alexandre Webster, Fan Zou, Jiamu Du, Dinshaw J Patel, Ravi Sachidanandam, Katalin Fejes Toth, Alexei a Aravin, Sisi Li

Cutoff suppresses RNA polymerase II termination to ensure expression of piRNA precursors

Yung-Chia Ariel Chen, Evelyn Stuwe, Yicheng Luo, Maria Ninova, Adrien Le Thomas, Ekaterina Rozhavskaya, Sisi Li, Sivani Vempati, John D Laver, Dinshaw J Patel

Aub and Ago3 are recruited to nuage through two mechanisms to form a ping-pong complex assembled by Krimper

Alexandre Webster, Sisi Li, Junho K Hur, Malte Wachsmuth, Justin S Bois, Edward M Perkins, Dinshaw J Patel, Alexei a Aravin

Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing

Adrien Le Thomas, Evelyn Stuwe, Sisi Li, Jiamu Du, Georgi Marinov, Nikolay Rozhkov, Yung-Chia Ariel Chen, Yicheng Luo, Ravi Sachidanandam, Katalin Fejes Toth