Sisi Li Research Group


The **Sisi Li Research Group** at Shenzhen University focuses on RNA homeostasis immunity. We integrate AI and structural biology to engineer functional RNAs and develop broad-spectrum antiviral strategies.

Latest News

Dec 2, 2020 2 min read
Jian Yang and Monica Hall Win the Best Paper Award at Wowchemy 2020
Jian Yang and Monica Hall Win the Best Paper Award at Wowchemy 2020

Congratulations to Jian Yang and Monica Hall for winning the Best Paper Award at the 2020 Conference on Wowchemy for their paper “Learning Wowchemy”.

Dec 1, 2020 2 min read
Richard Hendricks Wins First Place in the Wowchemy Prize
Richard Hendricks Wins First Place in the Wowchemy Prize

Congratulations to Richard Hendricks for winning first place in the Wowchemy Prize.

Decoding RNA immunity

Recent Publications

1. Yelan Xiao , Xiang Zhou , Nuo Cheng , Jianxin Ma , Jiacheng Yang , Jiarong Tian , Guolei Gao , Zhen Zhang , Mu-Peng Luo , Shou-Guo Wang , Sisi Li , Tong Shu , Xueji Zhang Morphological Programming in Gold (III) Coordination Assemblies via pH-Modulated Noncovalent Hierarchy. ACS Applied Materials & Interfaces, 18(19), 27946-27956 (2026).

2. Xuefei Wang , Meng Dong , Xinchao Wu , Daniel Schnepf , Julia Thiel , Wenfei Sun , Christian Wolfrum , Sisi Li , Wenfei Jin , Peter Staeheli Single-cell transcriptomics reveals a compartmentalized antiviral interferon response in the nasal epithelium of mice. Journal of Virology, 99(3), e01413-24 (2025).

3. Jun Yang , Reqing He , Zhipeng Qu , Jinbao Gu , Liyun Jiang , Xiangqiang Zhan , Ying Gao , David L Adelson , Sisi Li , Zhen-Yu Wang , Youlin Zhu , Dong Wang Long noncoding RNA ARTA controls ABA response through MYB7 nuclear trafficking in Arabidopsis. Developmental Cell, 58(13), 1206-1217 (2023).

4. Xuan Du , Zhenlin Yang , Guohui Xie , Changshi Wang , Laixing Zhang , Kaige Yan , Maojun Yang , Sisi Li , Jian-Kang Zhu , Jiamu Du Molecular basis of the plant ROS1-mediated active DNA demethylation. Nature Plants, 9(2), 271-279 (2023).

5. Guohui Xie , Xuan Du , Hongmiao Hu , Sisi Li , Xiaofeng Cao , Steven E Jacobsen , Jiamu Du Structure and mechanism of the plant RNA polymerase V. Science, 379(6638), 1209-1213 (2023).

See all publications